The Brain Sterol Atlas provides an interface for users to explore the concentrations of sterol lipids (~200) measured in 10 mouse brain regions. It could show the spatial distrubutions and concentrations of sterol lipids among different brain regions of mice. The concentrations of sterol lipids were measured by ion mobility-mass spectrometry (IM-MS) based four-dimensional sterolomics technology. The spatial maps of mouse brain were sourced from Allen Institute (https://atlas.brain-map.org/).
- E.S. Lein, et al. Genome-wide atlas of gene expression in the adult mouse brain, Nature, 2007, 445, 168–176.
- Q. Wang, S.L. Ding, Y. Li, et al. The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas. Cell. 2020, 181,936-953.
- T. Li, Y. Yin, Z. Zhou, J. Qiu, W. Liu, X. Zhang, K. He, Y. Cai, and Z.-J. Zhu* (corresponding author), Ion Mobility-based Sterolomics Reveals Spatially and Temporally Distinctive Sterol Lipids in Mouse Brain, Nature Communications, 2021, 12, 4343. https://doi.org/10.1038/s41467-021-24672-x